1049031-82-4Relevant academic research and scientific papers
One-pot Synthesis of Benzo[4,5]imidazo[1,2-a]pyridine Derivatives in Aqueous Conditions
Vodolazhenko, Maria A.,Mykhailenko, Anastasiia E.,Gorobets, Nikolay Yu.,Desenko, Sergey M.
, p. 753 - 757 (2017/02/03)
One-pot reaction of cyclic 1,3-diketones, dimethylformamide dimethylacetal (DMFDMA) and 2-(1H-benzo[d]imidaz-2-yl)acetonitrile was found to be a highly selective process leading to 4-oxo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]quinolin-6-yl cyanides. Op
Pathways for cyclizations of hydrazine-derived 2-(2-cyanovinyl)-3-oxo- cyclohex-1-ene enolates
Yermolayev, Sergey A.,Gorobets, Nickolay Yu.,Shishkin, Oleg V.,Shishkina, Svetlana V.,Leadbeater, Nicholas E.
experimental part, p. 2934 - 2941 (2011/05/13)
The introduction of a hydrazine functionality into 2-(2-cyanovinyl)-3-oxo- cyclohex-1-ene enolates results in their spontaneous cyclizations with participation of the hydrazine moiety. Depending on the reaction conditions used, the hydrazine-derived enola
Synthesis of novel 3-(1,3-thiazol-2-yl)-7,8-dihydroquinoline-2,5(1H,6H)- diones
Dzhavakhishvili,Gorobets,Chernenko,Musatov,Desenko
experimental part, p. 422 - 427 (2009/06/05)
An efficient method for the synthesis of novel 3-(1,3-thiazol-2-yl)-7,8- dihydroquinoline-2,5(1H,6H)-diones from various 2- dimethylaminomethylidenecyclohexane-1,3-diones, (1,3-thiazol-2-yl)acetonitriles, and dimethylformamide dimethyl acetal was developed. These transformations proceeded through intermediate 2-[2-(4-aryl-1,3-thiazol-2-yl)-2-cyanoethenyl]-3- oxocyclohex-1-en-1-olates. They were isolated as piperidinium salts and used in further heterocyclization reactions with aromatic amines, giving novel 1-aryl-3-(1,3-thiazol-2-yl)-7,8-dihydroquinoline-2,5(1H,6H)-diones. These compounds were also obtained by preparative three-step "one pot" synthesis under controlled microwave irradiation.
