104907-83-7

Basic information

• Product Name: 1-(2,4-Dichloro-phenyl)-2-imidazol-1-yl-ethanone O-(5-chloro-benzo[b]thiophen-2-ylmethyl)-oxime
• CAS NO: 104907-83-7
• Molecular Weight: 450.776
• Mol File: 104907-83-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2,4-Dichloro-phenyl)-2-imidazol-1-yl-ethanone O-(5-chloro-benzo[b]thiophen-2-ylmethyl)-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-Dichloro-phenyl)-2-imidazol-1-yl-ethanone O-(5-chloro-benzo[b]thiophen-2-ylmethyl)-oxime(104907-83-7)
• EPA Substance Registry System: 1-(2,4-Dichloro-phenyl)-2-imidazol-1-yl-ethanone O-(5-chloro-benzo[b]thiophen-2-ylmethyl)-oxime(104907-83-7)

Safety Data

• Hazardous Substances Data: 104907-83-7(Hazardous Substances Data)

Upstream product

• 100220-48-2 (Z)-1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone oxime 
• 99592-53-7 2-bromomethyl-5-chlorobenzo[b]thiophene 
• 64211-06-9 (Z)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-ethanone oxime 

Relevant articles and documents

Synthesis and antimycotic activity of (benzo[b]thienyl)methyl ethers of 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-ethanol and of (Z)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone oxime

A new series of (benzo[b]thienyl)methyl ethers of 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol and of (Z)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone oxime were synthesized and tested for antifungal activity. Series design, synthesis, preliminary antimycotic data and structure-activity relationships are reported. 7-Chloro-3-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxymethyl] benzo[b]thiophene (8i, Sertaconazole, FI-7045, CAS 99592-32-2) and its nitrate were selected for further research.