104909-40-2

Basic information

• Product Name: ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate
• Synonyms: ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate;5-Chloro-1-(2-pyrimidinyl)-1H-pyrazole-4-carboxylic acid ethyl ester
• CAS NO: 104909-40-2
• Molecular Formula: C10H9ClN4O2
• Molecular Weight: 252.65706
• Mol File: 104909-40-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 444.8 °C at 760 mmHg
• Flash Point: 222.8 °C
• Appearance: /
• Density: 1.45
• Vapor Pressure: 4.16E-08mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate(104909-40-2)
• EPA Substance Registry System: ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate(104909-40-2)

Safety Data

• Hazardous Substances Data: 104909-40-2(Hazardous Substances Data)

Usage

Description

Ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate is a complex organic chemical compound characterized by the presence of a pyrazole ring, a pyrimidine ring, and an ethyl ester group. It is recognized for its role in the synthesis of heterocyclic compounds and holds promise as a pharmaceutical intermediate for the development of novel drugs, with ongoing research exploring its full potential in the realms of chemistry and pharmaceutical science.

Uses

Used in Organic Chemistry:
Ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate is used as a reagent for the synthesis of various heterocyclic compounds, contributing to the advancement of organic chemistry through the creation of new chemical entities with potential applications in different fields.
Used in Pharmaceutical Science:
In the pharmaceutical industry, Ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate is utilized as a pharmaceutical intermediate. Its complex structure and chemical properties make it a candidate for the development of new drugs, with ongoing research aimed at uncovering its therapeutic potential and optimizing its use in medicinal chemistry.

InChI:InChI=1/C10H9ClN4O2/c1-2-17-9(16)7-6-14-15(8(7)11)10-12-4-3-5-13-10/h3-6H,2H2,1H3

Upstream product

• 1104275-51-5 ethyl 3-amino-1-pyrimidin-2-yl-1H-pyrazole-4-carboxylate 

Relevant articles and documents

5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS

5-Membered heterocyclic amides and related compounds are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly usef