1049672-75-4 Usage
General Description
1H-Pyrazolo[3,4-c]pyridin-5-amine, also known as CPP, is a chemical compound with potential therapeutic applications. It belongs to the class of pyrazolopyridine derivatives and has been studied for its pharmacological activities, particularly as a potential anti-cancer agent. Research has also identified its potential as a kinase inhibitor, which could make it a promising candidate for the development of new targeted cancer therapies. Additionally, it has been investigated for its role in the treatment of inflammatory and autoimmune diseases. Overall, 1H-Pyrazolo[3,4-c]pyridin-5-amine shows promise as a versatile and valuable chemical compound in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1049672-75-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,6,7 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1049672-75:
(9*1)+(8*0)+(7*4)+(6*9)+(5*6)+(4*7)+(3*2)+(2*7)+(1*5)=174
174 % 10 = 4
So 1049672-75-4 is a valid CAS Registry Number.
1049672-75-4Relevant articles and documents
NMR study of 5-substituted pyrazolo[3,4-c]pyridine derivatives
Tsikouris, Orestis,Bartl, Tomas,Tousek, Jaromir,Lougiakis, Nikolaos,Tite, Tony,Marakos, Panagiotis,Pouli, Nicole,Mikros, Emmanuel,Marek, Radek
, p. 643 - 649 (2008)
Substituted pyrazolopyridines are potent inhibitors of phosphodiesterases and cyclin-dependent kinases. In this study, NMR was used to investigate the potential NI-H and N2-H tautomerism of 5-substituted pyrazolo[3,4-c]pyridine derivatives. Six compounds were fully characterized by using 1H, 13C, and 15N chemical shifts and indirect 1H-13C and 1H-15N coupling constants. The 1H NMR spectra were measured over a broad range of temperatures. All of the compounds were shown to exist predominantly in the NI-H tautomeric form. Complementary quantum-chemical calculations of the chemical shieldings and indirect spin-spin couplings support the structural conclusions drawn. Copyright