1049672-77-6

Basic information

• Product Name: 1H-Pyrazolo[3,4-c]pyridin-5(6H)-one
• Synonyms: 1H-Pyrazolo[3,4-c]pyridin-5(6H)-one;1,6-Dihydro-pyrazolo[3,4-c]pyridin-5-one;1,6-Dihydro-5H-pyrazolo[3,4-c]pyridin-5-one
• CAS NO: 1049672-77-6
• Molecular Formula: C6H5N3O
• Molecular Weight: 135.1234
• Mol File: 1049672-77-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Pyrazolo[3,4-c]pyridin-5(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-c]pyridin-5(6H)-one(1049672-77-6)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-c]pyridin-5(6H)-one(1049672-77-6)

Safety Data

• Hazardous Substances Data: 1049672-77-6(Hazardous Substances Data)

Usage

Uses

1,6-Dihydro-5H-pyrazolo[3,4-c]pyridin-5-one is an aromatic heterocycle that can bind to heme iron in inhibition of cytochrome P450.

Upstream product

• 76006-07-0 5-methoxy-1H-pyrazolo[3,4-c]pyridine 

Relevant articles and documents

NMR study of 5-substituted pyrazolo[3,4-c]pyridine derivatives

Substituted pyrazolopyridines are potent inhibitors of phosphodiesterases and cyclin-dependent kinases. In this study, NMR was used to investigate the potential NI-H and N2-H tautomerism of 5-substituted pyrazolo[3,4-c]pyridine derivatives. Six compounds were fully characterized by using 1H, 13C, and 15N chemical shifts and indirect 1H-13C and 1H-15N coupling constants. The 1H NMR spectra were measured over a broad range of temperatures. All of the compounds were shown to exist predominantly in the NI-H tautomeric form. Complementary quantum-chemical calculations of the chemical shieldings and indirect spin-spin couplings support the structural conclusions drawn. Copyright