1049678-66-1

Basic information

• Product Name: 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethanol
• Synonyms: 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethanol;2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol
• CAS NO: 1049678-66-1
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.21384
• EINECS: -0
• Mol File: 1049678-66-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethanol(1049678-66-1)
• EPA Substance Registry System: 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethanol(1049678-66-1)

Safety Data

• Hazardous Substances Data: 1049678-66-1(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Constituent rings

Pyridine and pyrazole rings

Functional group

Ethanol functional group

Pharmaceutical applications

Modulation of biological pathways and interactions

Potential use in drug development

Diseases related to modulated pathways

Industrial applications

Chemical reactions and synthesis

Research needs

Further studies to assess therapeutic properties and potential uses

Evaluation

Understanding and evaluating the effects in various fields

Upstream product

• 109-84-2 2-hydroxyethylhydrazine 
• 75415-00-8 (Z)-3-(dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one 

Downstream Products

• 1049678-69-4 4-(2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethoxy)-6-chloro-N,N-diphenyl-1,3,5-triazin-2-amine 

Relevant articles and documents

A copper complex bearing a TEMPO moiety as catalyst for the aerobic oxidation of primary alcohols

A new bifunctional, triazine-based ligand has been designed with the aim to generate a copper(ii) complex holding a TEMPO (2,2,6,6- tetramethylpiperidinyloxy) moiety. The coordination compound obtained from the ligand 4-(2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)ethoxy)-6-(4-amino-2,2,6,6- tetramethylpiperidine-1-oxyl)-N,N-diphenyl-1,3,5-triazin-2-amine (pypzt-1) and copper(ii) bromide (i.e. complex 8) is capable of catalysing the selective, aerobic oxidation of benzyl alcohol to 84% of benzaldehyde in 24 h. This galactose oxidase activity of the copper/TEMPO complex is observed as well for the conversion of the non-activated alkyl alcohol octan-1-ol to octanal with a yield of 29% after the same reaction time. The single-crystal X-ray structure of 8 shows that its crystal lattice contains [Cu IBr2]- anions which appear to be stabilised by means of both anion-π and hydrogen bonding interactions. In addition, the solid state structure of 8 exhibits (lone-pair)-π interactions between the nitrogen atom of an acetonitrile molecule and a triazine ring. The magnetic properties of 8 have been investigated by EPR and magnetic susceptibility measurements.