1049693-98-2 Usage
General Description
(4-{[(4-methylphenyl)sulfonyl]oxy}phenyl)boronic acid is a chemical compound consisting of a boronic acid group attached to a phenyl ring with an attached sulfonyloxy group, which in turn is linked to a methylphenyl group. It is used in organic synthesis as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, particularly in the Suzuki-Miyaura cross-coupling reaction. The boronic acid functionality allows for the formation of stable complexes with Lewis bases, making it useful in catalysis and as a ligand in metal-catalyzed reactions. The presence of the sulfonyloxy group and the aromatic rings also give this compound potential for use as a pharmacophore in medicinal chemistry and drug discovery. Overall, (4-{[(4-methylphenyl)sulfonyl]oxy}phenyl)boronic acid is a versatile and valuable compound with applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1049693-98-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,6,9 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1049693-98:
(9*1)+(8*0)+(7*4)+(6*9)+(5*6)+(4*9)+(3*3)+(2*9)+(1*8)=192
192 % 10 = 2
So 1049693-98-2 is a valid CAS Registry Number.
1049693-98-2Relevant articles and documents
Preparation method of hydroxyphenylboronic acid
-
Paragraph 0050; 0052, (2020/05/08)
The invention discloses a preparation method of hydroxyphenylboronic acid, which belongs to the technical field of boric acid synthesis in medical intermediates. The method comprises the following steps: starting from bromophenol, carrying out BOC, trimethylsilyl or benzyl protection, forming a Grignard reagent, reacting with borate, or carrying out one-pot reaction with borate and n-butyllithium,and hydrolyzing to obtain hydroxyphenylboronic acid. According to the invention, cheap and easily available protecting groups are adopted, so that the protecting groups are easy to remove during boronation reaction hydrolysis, industrial amplification is easy to realize, batch production is carried out on the scale of dozens of kilograms, and the process stability is good.
