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tert-butyl [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl](methyl)carbamate is a degradation product of phenylephrine, a selective α1-adrenergic receptor agonist. It is characterized by its chiral center at the 2-position and the presence of hydroxyl groups on both the phenyl and ethyl moieties. tert-butyl [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl](methyl)carbamate has potential applications in various fields due to its unique structure and properties.

1049702-99-9

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1049702-99-9 Usage

Uses

Used in Pharmaceutical Industry:
tert-butyl [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl](methyl)carbamate is used as an intermediate in the synthesis of pharmaceutical compounds. Its chiral center and functional groups can be exploited for the development of enantioselective catalysts or chiral ligands, which are essential for the production of enantiomerically pure drugs.
Used in Chemical Research:
tert-butyl [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl](methyl)carbamate can be used as a building block or a starting material in the synthesis of various organic compounds, particularly those with chiral centers and multiple functional groups. Its reactivity and selectivity can be studied to develop new synthetic methods and strategies.
Used in Analytical Chemistry:
Due to its unique structure and chiral properties, tert-butyl [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl](methyl)carbamate can be employed as a chiral derivatizing agent for the enantiomeric analysis of chiral compounds by chromatographic or spectroscopic techniques.
Used in Material Science:
tert-butyl [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl](methyl)carbamate's functional groups and chiral nature can be utilized in the development of new materials with specific properties, such as chiral polymers, liquid crystals, or self-assembling systems.

Check Digit Verification of cas no

The CAS Registry Mumber 1049702-99-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,7,0 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1049702-99:
(9*1)+(8*0)+(7*4)+(6*9)+(5*7)+(4*0)+(3*2)+(2*9)+(1*9)=159
159 % 10 = 9
So 1049702-99-9 is a valid CAS Registry Number.

1049702-99-9Relevant academic research and scientific papers

Syntheses of potential degradation products of phenylephrine in OTC products

Chan,Kong, Jianshe,McNamara, Paul,Wong, Jesse K.

, p. 2252 - 2260 (2008/09/21)

Compound 1 and 2 are potential major degradants in over the counter (OTC) products containing phenylephrine HCl and dexbrompheniramine maleate or chlorpheniramine maleate. Compound 2 matches the unknown peak in the solution of stressed active and excipient and thus was identified as the correct degradation product. Whether the degradation product is racemic or chiral is not known. This article describes synthesis of both compounds. Compound 2 will be useful as an analytical standard for quantitative analysis of the major degradant in OTC products of phenylephrine HCl and dexbrompheniramine maleate or chlorpheniramine maleate. Copyright Taylor & Francis Group, LLC.

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