104977-33-5

Upstream product

• 865-50-9 iodomethane-d3 
• 536-74-3 phenylacetylene 

Downstream Products

• 50848-69-6 1,1,1-trideuterio-3-phenyl-propan-2-one 
• 119458-35-4 β-trideuterio-propiophenone 
• 134839-89-7 (3,3,3-trideuterio-propyl)-benzene 
• 1440664-91-4 C₁₄H₁₁⁽²⁾HOS 

Relevant academic research and scientific papers

Pd-catalyzed C-H olefination of (hetero)arenes by using saturated ketones as an olefin source

Tolerant: By using Pd(OAc)2/PCy3 as a catalyst, both electron-rich aromatic heterocycles and electron-deficient fluorobenzenes undergo the dehydrogenative cross-coupling with (hetero)aryl ethyl ketones in good yields. A broad range of functional groups is tolerated, thus providing a general method for the facile syntheses of chalcones or heterocyclic chalcone analogues. Furthermore, dialkyl ketones can also participate in this transformation. Copyright

A Correlation between β-Hydrogen Isotope Effects on Carbon-13 NMR Chemical Shifts in Unsaturated Systems and the Strength of Hyperconjugative Interactions

β-Hydrogen isotope effects on the carbon-13 NMR chemical shifts of the trigonal carbon in CL3C(R)=X (L=H, or D) are reported for 15 substances inwhich the positive charge density at the trigonal carbon is regulated through systematic variation of R and X.A linear relationship is found between these isotope effects and the chemical shifts of the trigonal carbons, and this is taken as evidence for dependence of the magnitude of these isotope effects upon the strength of the hyperconjugative interaction between CL3 and C(R)=X.An explanation of hyperconjugative NMR isotope effecs in terms of anharmonic carbon-hydrogen bond-bending vibrations is advanced.