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1049808-01-6

3-(4-Chloro-3-cyclohexylethynyl-phenyl)-5-methanesulfonyl-1-(3-morpholin-4-yl-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 3-(4-Chloro-3-cyclohexylethynyl-phenyl)-5-methanesulfonyl-1-(3-morpholin-4-yl-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine

    Cas No: 1049808-01-6

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  • 1049808-01-6 Structure

  • Basic information

    1. Product Name: 3-(4-Chloro-3-cyclohexylethynyl-phenyl)-5-methanesulfonyl-1-(3-morpholin-4-yl-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine
    2. Synonyms:
    3. CAS NO:1049808-01-6
    4. Molecular Formula:
    5. Molecular Weight: 545.146
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1049808-01-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(4-Chloro-3-cyclohexylethynyl-phenyl)-5-methanesulfonyl-1-(3-morpholin-4-yl-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(4-Chloro-3-cyclohexylethynyl-phenyl)-5-methanesulfonyl-1-(3-morpholin-4-yl-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine(1049808-01-6)
    11. EPA Substance Registry System: 3-(4-Chloro-3-cyclohexylethynyl-phenyl)-5-methanesulfonyl-1-(3-morpholin-4-yl-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine(1049808-01-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1049808-01-6(Hazardous Substances Data)

1049808-01-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1049808-01-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,8,0 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1049808-01:
(9*1)+(8*0)+(7*4)+(6*9)+(5*8)+(4*0)+(3*8)+(2*0)+(1*1)=156
156 % 10 = 6
So 1049808-01-6 is a valid CAS Registry Number.

1049808-01-6Downstream Products

1049808-01-6Relevant articles and documents

Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements

Ameriks, Michael K.,Axe, Frank U.,Bembenek, Scott D.,Edwards, James P.,Gu, Yin,Karlsson, Lars,Randal, Mike,Sun, Siquan,Thurmond, Robin L.,Zhu, Jian

, p. 6131 - 6134 (2009)

A crystal structure of 1 bound to a Cys25Ser mutant of cathepsin S helped to elucidate the binding mode of a previously disclosed series of pyrazole-based CatS inhibitors and facilitated the design of a new class of arylalkyne analogs. Optimization of the

CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S

-

Page/Page column 28, (2008/12/08)

Carbon-linked tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.

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