1049809-45-1Relevant academic research and scientific papers
Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: Optimization of cellular potency
Ameriks, Michael K.,Cai, Hui,Edwards, James P.,Gebauer, Damara,Gleason, Elizabeth,Gu, Yin,Karlsson, Lars,Nguyen, Steven,Sun, Siquan,Thurmond, Robin L.,Zhu, Jian
scheme or table, p. 6135 - 6139 (2010/06/16)
Basic lipophilic substituents dramatically improved the cellular potency of a previously disclosed series of pyrazole-based arylalkyne cathepsin S inhibitors. The incorporation of substituted benzylamines in the para position of the arylalkyne maintained
