104987-10-2Relevant articles and documents
Synthesis of the Novel Sarkosine and Proline (FK-525) Analogues of FK-506: Rearrangement of the Allylic Ester System
Askin, D.,Reamer, R. A.,Joe, Daisy,Volante, R. P.,Shinkai, I.
, p. 5448 - 5450 (2007/10/02)
The novel sarcosine 2 and proline 3 (FK-525) analogues of FK-506 have been synthesized.Allylic rearranged products not observed in the pipecolinic acid series have been isolated from the amino acid formation/macrocyclization step.