104995-47-3

Upstream product

• 98993-13-6 (E)-3-(6-Formyl-6-methyl-cyclohex-2-enyl)-but-2-enoic acid methyl ester 
• 882-33-7 diphenyldisulfane 

Downstream Products

• 105086-97-3 Toluene-4-sulfonic acid (E)-3-{(5R,6R)-3-[(1S,2S)-2-((E)-3-benzenesulfonyl-1-methyl-propenyl)-1-methyl-cyclohex-3-enecarbonyl]-4-methoxy-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-allyl ester 
• 104995-50-8 Toluene-4-sulfonic acid (E)-3-{(5R,6R)-3-[(1R,2R)-2-((E)-3-benzenesulfonyl-1-methyl-propenyl)-1-methyl-cyclohex-3-enecarbonyl]-4-methoxy-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-allyl ester 
• 104995-62-2 Toluene-4-sulfonic acid (E)-3-{(5R,6R)-4-methoxy-3-[(1S,2S)-1-methyl-2-((E)-1-methyl-3-phenylsulfanyl-propenyl)-cyclohex-3-enecarbonyl]-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-allyl ester 
• 104995-62-2 Toluene-4-sulfonic acid (E)-3-{(5R,6R)-4-methoxy-3-[(1R,2R)-1-methyl-2-((E)-1-methyl-3-phenylsulfanyl-propenyl)-cyclohex-3-enecarbonyl]-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-allyl ester 
• 104995-52-0 (E)-3-{(5R,6R)-3-[(1R,2R)-2-((E)-3-Benzenesulfonyl-1-methyl-propenyl)-1-methyl-cyclohex-3-enecarbonyl]-4-methoxy-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-acrylic acid methyl ester 
• 104995-53-1 C₃₂H₃₄O₇S 
• 104995-54-2 (E)-3-{(5R,6R)-3-[(1R,2R)-2-((E)-3-Benzenesulfonyl-1-methyl-propenyl)-1-methyl-cyclohex-3-enecarbonyl]-4-methoxy-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-propenal 
• 104995-55-3 C₃₂H₃₆O₇S 
• 104995-56-4 C₃₂H₃₄O₇S 
• 104995-63-3 (E)-3-{(5R,6R)-4-Methoxy-3-[(1R,2R)-1-methyl-2-((E)-1-methyl-3-phenylsulfanyl-propenyl)-cyclohex-3-enecarbonyl]-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-acrylic acid methyl ester 
• 105018-31-3 C₃₂H₃₆O₆S 
• 104995-51-9 (E)-3-{(5R,6R)-4-Methoxy-3-[(1R,2R)-1-methyl-2-((E)-1-methyl-3-phenylsulfanyl-propenyl)-cyclohex-3-enecarbonyl]-2-oxo-1-oxa-spiro[4.5]deca-3,8-dien-6-yl}-2-methyl-propenal 
• 104995-49-5 (5R,10R)-10-((E)-3-Hydroxy-2-methyl-propenyl)-4-methoxy-3-[(1R,2R)-1-methyl-2-((E)-1-methyl-3-phenylsulfanyl-propenyl)-cyclohex-3-enecarbonyl]-1-oxa-spiro[4.5]deca-3,7-dien-2-one 
• 105086-96-2 (5R,10R)-10-((E)-3-Hydroxy-2-methyl-propenyl)-4-methoxy-3-[(1S,2S)-1-methyl-2-((E)-1-methyl-3-phenylsulfanyl-propenyl)-cyclohex-3-enecarbonyl]-1-oxa-spiro[4.5]deca-3,7-dien-2-one 

Relevant academic research and scientific papers

A Synthetic Approach to the Macrolide Nucleus of Tetronolide

Synthesis of compound 4, the 14-membered macrolide nucleus of tetronolide (1), has been achieved via a base-catalyzed intramolecular cyclization of α-sulfonyl ω-aldehyde 15a under controlled conditions.