1050-75-5Relevant academic research and scientific papers
Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases
Domínguez, Marta,Pequerul, Raquel,Alvarez, Rosana,Giménez-Dejoz, Joan,Birta, Eszter,Porté, Sergio,Rühl, Ralph,Parés, Xavier,Farrés, Jaume,de Lera, Angel R.
, p. 2567 - 2574 (2018/04/19)
A new synthesis of three apocarotenoids, namely 14′-apo-β-carotenal, 12′-apo-β-carotenal and 10′-apo-β-carotenal, has been achieved that is based on the acyclic cross-metathesis of the hexaene derived from retinal and the corresponding partners. These compounds can be enzymatically converted to their carboxylic acids by the human aldehyde dehydrogenases involved in retinaldehyde oxidation. Their kinetic parameters suggest that these enzymes might play a role in the physiological metabolism of apocarotenoids.
Total Synthesis of Acetylenic Carotenoids. 2. Synthesis of (all-E)-(3R,3'R)-Diatoxanthin and (all-E)-(3R)-7,8-Didehydrocryptoxanthin
Haugan, Jarle Andre,Liaaen-Jensen, Synnoeve
, p. 899 - 904 (2007/10/02)
Optically active (all-E)-(3R,3'R)-diatoxanthin, indistinguishable from the natural carotenol, has been prepared by total synthesis for the first time with 34percent overall yield in four steps from the available (2E)-5-(4R)-4-hydroxy-2,6,6-trimethylcyclo
Electronic Relaxation in Long Polyenes
Cosgrove, Sarah A.,Guite, Melissa A.,Burnell, Timothy B.,Christensen, Ronald L.
, p. 8118 - 8124 (2007/10/02)
A series of carotenols with from 7 to 11 conjugated double bonds have been synthesized and purified using HPLC techniques.Absorption, fluorescence, and fluorescence excitation spectra have been obtained in 77 K glasses.The shorter members of this series e
