105016-64-6

Upstream product

• 34987-31-0 2‐cyclohexylnaphthalene‐1,4‐dione 
• 34491-88-8 2-butyl-1,4-naphthoquinone 

Relevant academic research and scientific papers

Catalytic asymmetric epoxidation of naphthoquinone derivatives under phase-transfer catalyzed conditions

2-Alkyl-1,4-naphthoquinones were smoothly transformed to the corresponding epoxides in moderate to good yields with good enantioselectivities (up to 76% ee) under mild reaction conditions by use of a catalytic amount of chiral quaternary ammonium salts de

THE EFFECT OF ORGANIC COSOLVENTS ON THE ENANTIOSELECTIVITY IN THE BOVINE SERUM ALBUMIN CATALYZED WEITZ-SCHEFFER CONDENSATION

Water miscible or immiscible organic cosolvents can strongly influence the enantioselectivity of the Weitz-Scheffer condensation catalyzed by bovine serum albumin, the enantiomeric excess (e.e.) being in the range 0-90percent.

CATALYTIC ASYMMETRIC WEITZ-SCHEFFER EPOXIDATION PROMOTED BY BOVINE SERUM ALBUMIN. PART II.

The epoxidation of 2 and 2,3-substituted naphthoquinones with t-BuOOH in aqueous buffer solutions, in the presence of bovine serum albumin (BSA) as chiral catalyst, affords the corresponding epoxynaphthoquinones with enantiomeric excess (e.e) up to 79perc

Enantioselective epoxidation of 2-substituted 1,4-naphthoquinones using gem-dihydroperoxides

New gem-dihydroperoxides were successfully used for DBU-promoted enantioselective epoxidation of 2-substituted 1,4-naphthoquinones. The corresponding 1,4-naphthoquinone epoxides were obtained in yields up to 97% and ee's up to 82%.

Catalytic asymmetric epoxidation of enones under phase-transfer catalyzed conditions

The development of the catalytic asymmetric epoxidation of enones promoted by aqueous H2O2 with chiral quaternary ammonium salts is described. The reaction smoothly proceeded to give α,β-epoxyketones with satisfactory enantioselectivities in both the trans and cis enone systems (up to 92% ee) by use of cinchonine or quinidine derivatives (5 mol%) as phase transfer catalysts.

The enantioselective epoxidation of quinones using sugar hydroperoxides

Sugar-derived hydroperoxides have been employed for DBU-promoted enantioselective epoxidation reactions. Optimisation studies are reported using 2-(5-cyclohexylpentadienamido)-1,4-benzoquinone (maximum ee = 67%); the resulting epoxide is an important synt

ASYMMETRIC WEITZ - SCHEFFER EPOXIDATION PROMOTED BY BOVINE SERUM ALBUMIN. PART III. HIGHLY STEREOELECTIVE SYNTHESIS OF OPTICALLY ACTIVE EPOXYNAPHTHOQUINONES.

The epoxidation of 2-substituted naphthoquinones with t-BuOOH in an aqueous buffer solution containing a small amount (up to 5 percent molar equiv) of bovine serum albumin (BSA) gives the corresponding epoxides with enantiomeric excess (e.e.) up to 100 pe

CATALYTIC ASYMMETRIC WEITZ-SCHEFFER REACTION IN THE PRESENCE OF BOVINE SERUM ALBUMIN

Epoxidation of 2-substituted 1,4-naphthoquinones with t-BuOOH or H2O2 in the presence of a catalytic amount of bovine serum albumin afforded the corresponding epoxynaphthoquinones in up 70percent e.e.