Cas 105018-52-8,Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

105018-52-8

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Product Name: Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester
Synonyms:
CAS NO:105018-52-8
Molecular Formula:
Molecular Weight: 934.039
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester(105018-52-8)
EPA Substance Registry System: Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester(105018-52-8)

Safety Data

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Safety Statements: N/A
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RTECS:
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Hazardous Substances Data: 105018-52-8(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 105018-52-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,0,1 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 105018-52:
(8*1)+(7*0)+(6*5)+(5*0)+(4*1)+(3*8)+(2*5)+(1*2)=78
78 % 10 = 8
So 105018-52-8 is a valid CAS Registry Number.

105018-52-8Upstream product

105018-52-8Downstream Products

118362-04-2 C₄₅H₅₂N₅O₁₅P*H₃N

105018-52-8Relevant academic research and scientific papers

Some Steric Aspects of Synthesis of Oligoribonucleotides by Phosphoramidite Approach on Solid Support

Kierzek, Ryszard,Rozek, Marek,Markiewicz, Wojciech T.

, p. 507 - 516 (2007/10/02)

The influence of 2'-O-substituents (i.e. methyl, tetrahydropyranyl, tert-butyldimethylsilyl) on the chemical synthesis of oligoribonucleotides by phosphoramidite approach on solid support is described and compared with respective 2'-deoxynucleoside derivative.The observations on reactivity of these different 2'-O-protected derivatives at phosphatilation and condensation steps show their strong hindrance dependence.Some other aspects like reactivity of tetrahydropyranyl diastereoisomers, 3'- and 2'-O-phosphoramidites and some chemical properties of 2'-O-(tert-butyldimethylsilyl) protecting group are also presented.

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