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Phenol,4-(aminomethyl)-2-ethoxy-, hydrochloride (1:1), also known as guaifenesin, is a chemical compound that features a phenolic ring with an ethoxy group and an aminomethyl group. It is widely recognized for its pharmaceutical applications, particularly as an expectorant, and is commonly found in the hydrochloride salt form for use in various formulations.

105026-85-5

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105026-85-5 Usage

Uses

Used in Pharmaceutical Industry:
Phenol,4-(aminomethyl)-2-ethoxy-, hydrochloride (1:1) is used as an expectorant for the treatment of respiratory conditions. It functions by increasing the volume and reducing the viscosity of respiratory tract secretions, facilitating the expulsion of mucus through coughing. This makes it an effective treatment for conditions such as bronchitis, asthma, pneumonia, and congestion caused by the common cold or flu.
The hydrochloride form of guaifenesin enhances its solubility and absorption when administered orally, ensuring its efficacy in therapeutic applications. Its widespread use in over-the-counter medications underscores its importance in managing respiratory symptoms and improving patient comfort.

Check Digit Verification of cas no

The CAS Registry Mumber 105026-85-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,0,2 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 105026-85:
(8*1)+(7*0)+(6*5)+(5*0)+(4*2)+(3*6)+(2*8)+(1*5)=85
85 % 10 = 5
So 105026-85-5 is a valid CAS Registry Number.

105026-85-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-ethoxy-4-aminomethyl-phenol, hydrochloride

1.2 Other means of identification

Product number -
Other names Hydrochloride, 2-Aethoxy-4-aminomethyl-phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105026-85-5 SDS

105026-85-5Downstream Products

105026-85-5Relevant articles and documents

Efficient hydrogenation of benzaldoximes and Schiff bases on ceramic high-porosity palladium catalysts

Ignatov,Varakutin,Solov’eva,Karmanova,Kozlov,Semenova,Semenov

, p. 1394 - 1400 (2018)

An efficient catalytic method for the synthesis of benzyl- and dibenzylamines by hydrogenating oximes and Schiffbases was developed on palladium supported high-porosity foamed ceramic block catalyst. The multiple regeneration ability of the foamed ceramic block catalyst can significantly decrease the Pd consumption as compared to the use of the conventional 10%Pd/C catalyst. Owing to a high hardness of the foamed ceramic catalyst, the reaction mixture can rapidly be removed from the reactor without using filtering devices. The structures produced by the reaction are fragments of biologically active and natural molecules. Antiproliferative properties of dibenzylamines revealed on the sea urchin embryo model suggest that these compounds can be considered as promising agents for the design of new anticancer drugs.

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