1050335-62-0

Upstream product

• 807626-25-1 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 108735-94-0 1-Ethyl 4-methyl 2-hydroxy 3-methylenebutanedioate 
• 807626-29-5 (3R,4S,1'S)-3-hydroxy-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 807626-23-9 1-ethyl-4-methyl-2-tert-butyldimethylsilyloxy-3-methylenebutanedioate 
• 807626-28-4 (3R,4R,1'S)-3-hydroxy-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 

Downstream Products

• 807626-30-8 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-tert-butyldimethylsilyloxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 267421-93-2 (3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidine 
• 807626-31-9 (3R,4R,1'S)-3-acetoxy-4-acetoxymethyl-1-(1'-phenylethyl)pyrrolidine 

Relevant academic research and scientific papers

Chiral 3-hydroxypyrrolidin-2-ones from a Baylis-Hillman adduct: Convergent, stereoselective synthesis of a glycosidase inhibitor

The O-silyl derivative 4b, prepared starting from the Baylis-Hillman adduct 4a, underwent cyclization on treatment with (S)-phenylethylamine, to give to an equimolar mixture of the 4,5-cis-disubstituted pyrrolidin-2-ones 9 and 10, exclusively, which after