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Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

105039-48-3

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105039-48-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 105039-48-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,0,3 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 105039-48:
(8*1)+(7*0)+(6*5)+(5*0)+(4*3)+(3*9)+(2*4)+(1*8)=93
93 % 10 = 3
So 105039-48-3 is a valid CAS Registry Number.

105039-48-3Downstream Products

105039-48-3Relevant academic research and scientific papers

Some Steric Aspects of Synthesis of Oligoribonucleotides by Phosphoramidite Approach on Solid Support

Kierzek, Ryszard,Rozek, Marek,Markiewicz, Wojciech T.

, p. 507 - 516 (2007/10/02)

The influence of 2'-O-substituents (i.e. methyl, tetrahydropyranyl, tert-butyldimethylsilyl) on the chemical synthesis of oligoribonucleotides by phosphoramidite approach on solid support is described and compared with respective 2'-deoxynucleoside derivative.The observations on reactivity of these different 2'-O-protected derivatives at phosphatilation and condensation steps show their strong hindrance dependence.Some other aspects like reactivity of tetrahydropyranyl diastereoisomers, 3'- and 2'-O-phosphoramidites and some chemical properties of 2'-O-(tert-butyldimethylsilyl) protecting group are also presented.

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