1050392-22-7

Basic information

• Product Name: (E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide
• Synonyms: (E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide;3-Amino-3-(4-methoxyphenyl)-2-methyl-2-propenethioamide;2-PropenethioaMide, 3-aMino-3-(4-Methoxyphenyl)-2-Methyl-;3-Amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide
• CAS NO: 1050392-22-7
• Molecular Formula: C₁₁H₁₄N₂OS
• Molecular Weight: 222.30666
• Mol File: 1050392-22-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.192
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide(1050392-22-7)
• EPA Substance Registry System: (E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide(1050392-22-7)

Safety Data

• Hazardous Substances Data: 1050392-22-7(Hazardous Substances Data)

Usage

General Description

"(E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide" is a chemical compound with the molecular formula C11H15NOS. It is a thioamide derivative and contains an amino group, a methyl group, and a methoxyphenyl group. (E)-3-amino-3-(4-methoxyphenyl)-2-methylprop-2-enethioamide may have applications in organic synthesis, pharmaceutical research, and biochemistry. Its specific properties and potential uses would need to be determined through further study and experimentation.

InChI:InChI=1S/C11H14N2OS/c1-7(11(13)15)10(12)8-3-5-9(14-2)6-4-8/h3-6H,12H2,1-2H3,(H2,13,15)/b10-7-

Upstream product

• 1050392-15-8 C₁₁H₁₂N₂O 
• 62-55-5 thioacetamide 
• 874-90-8 4-methoxybenzonitrile 

Downstream Products

• 1050392-29-4 3-(4-methoxy-phenyl)-4-methylisothiazol-5-ylamine 

Relevant articles and documents

3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity

The disclosed 3-phenyl-5-isothiazole carboxamides are potent allosteric antagonists of mGluR1 with generally good selectivity relative to the related group 1 receptor mGluR5. Pharmacokinetic properties of a member of this series (1R,2R)-N-(3-(4-methoxyphenyl)-4-methylisothiazol-5-yl)-2- methylcyclopropanecarboxamide (14) are good, showing acceptable plasma and brain exposure after oral dosing. Oral administration of isothiazole 14 gave robust activity in the formalin model of persistent pain which correlated with CNS receptor occupancy.