1050442-14-2Relevant academic research and scientific papers
Synthesis and antitumor activity of novel α-aminophosphonates from diterpenic dehydroabietylaminer
Rao, Xiaoping,Song, Zhanqian,He, Ling
, p. 512 - 516 (2008/12/22)
A series of novel α-aminophosphonates were synthesized from diterpenic dehydroabietylamine, and their structures were characterized by IR, 1H NMR, and 31P NMR spectroscopy. Their antitumor activities against SMMC7721 liver cancer cells were evaluated by the MTT method. Compounds 4 and 6 exhibited higher activities even at very low concentrations, and the inhibition ratios reached 75% and 79% at 0.1 μM, respectively. The inhibition ratio of compound 9 reached 99% after 72-h incubation. α-Aminophosphonates with a fluorine atom and a nitro group fused to the benzene ring exhibited higher activities.
Synthesis and biological activity of Schiff bases derived from dehydroabietylamine and benzaldehyde derivatives
Zhao, Xiaoping,Song, Dzen Kwang,Radbil',Radbil'
, p. 1373 - 1375 (2008/03/13)
Previously unknown Schiff bases were prepared from dehydroabietylamine and substituted benzaldehydes. Their physicochemical properties were determined, and the bactericidal activity toward some microorganisms was evaluated.
