Cas 1050442-32-4,C19H17N3O2S

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Check Digit Verification of cas no

The CAS Registry Mumber 1050442-32-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,0,4,4 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1050442-32:
(9*1)+(8*0)+(7*5)+(6*0)+(5*4)+(4*4)+(3*2)+(2*3)+(1*2)=94
94 % 10 = 4
So 1050442-32-4 is a valid CAS Registry Number.

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1050442-32-4Relevant academic research and scientific papers

Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors

Janetka, James W.,Almeida, Lynsie,Ashwell, Susan,Brassil, Patrick J.,Daly, Kevin,Deng, Chun,Gero, Thomas,Glynn, Roberta E.,Horn, Candice L.,Ioannidis, Stephanos,Lyne, Paul,Newcombe, Nicholas J.,Oza, Vibha B.,Pass, Martin,Springer, Stephanie K.,Su, Mei,Toader, Dorin,Vasbinder, Melissa M.,Yu, Dingwei,Yu, Yan,Zabludoff, Sonya D.

, p. 4242 - 4248 (2008)

Checkpoint kinase-1 (Chk1, CHEK1) is a Ser/Thr protein kinase that mediates the cellular response to DNA-damage. A novel class of 2-ureido thiophene carboxamide urea (TCU) Chk1 inhibitors is described. Inhibitors in this chemotype were optimized for cellular potency and selectivity over Cdk1.

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