1050443-70-3Relevant academic research and scientific papers
Aminomethylation of chiral silyl enol ethers: access to β2-homotryptophane and β2-homolysine derivatives
Moumné, Roba,Larregola, Maud,Boutadla, Youcef,Lavielle, Solange,Karoyan, Philippe
, p. 4704 - 4707 (2008)
We describe here the aminomethylation of chiral silyl enol ether derivatives using iminium ion. The choice of judicious precursors with adequate protecting groups for the silylation/aminomethylation step was required to achieve the synthesis of β2-homotryptophane in few steps. The same methodology was used to prepare a β2-homolysine derivative.
