1050445-63-0 Usage
Type of compound
Fluoroalkanol derivative
Contains
Trifluoromethyl group, nitrophenyl group, and hydroxyl group
Use
Building block in organic synthesis and pharmaceutical research
Known for
High reactivity
Common use
Reagent for introducing trifluoromethyl group into organic molecules
Potential applications
Development of new drugs and agrochemicals
Unique characteristic
Unique chemical properties
Check Digit Verification of cas no
The CAS Registry Mumber 1050445-63-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,0,4,4 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1050445-63:
(9*1)+(8*0)+(7*5)+(6*0)+(5*4)+(4*4)+(3*5)+(2*6)+(1*3)=110
110 % 10 = 0
So 1050445-63-0 is a valid CAS Registry Number.
1050445-63-0Relevant academic research and scientific papers
Catalytic enantioselective addition of diethylzinc to trifluoromethyl ketones
Yearick, Kimberly,Wolf, Christian
supporting information; experimental part, p. 3915 - 3918 (2009/05/31)
(Figure Presented) A procedure for nucleophilic addition of diethylzinc to trifluoramethyl ketones was developed. The TMEDA-catalyzed method converts aromatic substrates to the corresponding 2-aryl-1,1,1-trifluorobutan-2-ols in up to 99% yield, and it is also applicable to less reactive aliphatic ketones if stoichiometric ligand amounts are employed. The first asymmetric variant producing tertiary alcohols with up to 61% ee when TBOX is used as catalyst is described.
