1050481-64-5Relevant articles and documents
Novel 1,4-benzothiazine derivatives as large conductance Ca 2+-activated potassium channel openers
Calderone, Vincenzo,Spogli, Roberto,Martelli, Alma,Manfroni, Giuseppe,Testai, Lara,Sabatini, Stefano,Tabarrini, Oriana,Cecchetti, Violetta
experimental part, p. 5085 - 5092 (2009/08/09)
The design and synthesis of a novel class of 1,4-benzothiazines targeted for the large-conductance calcium-activated potassium channels (BK) are presented. In vitro functional characterization of BK channel opening activity was assessed by measuring the r