FMoc-α-Me-Gly(Pentynyl)-OH, also known as N-(9-fluorenylmethoxycarbonyl)-alpha-methylglycine (Pent-1-yn-1-yl) ester, is a chemical compound with the molecular formula C26H23NO4. It is a derivative of the amino acid glycine, featuring a pentynyl group attached to the alpha carbon. FMoc-α-Me-Gly(Pentynyl)-OH is widely utilized in the fields of peptide synthesis and solid-phase peptide synthesis, thanks to its ability to protect the amino group and facilitate selective reactions at the carboxylic acid group. Additionally, it holds promise for the development of pharmaceuticals and bioactive compounds.
1050501-65-9
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Basic information
- Product Name: FMoc-α-Me-Gly(Pentynyl)-OH
- Synonyms: FMoc-α-Me-Gly(Pentynyl)-OH;Fmoc-alpha-Me-D-Ala(Pentynyl)-OH;6-Heptynoic acid, 2-[[(9H-fluoren-9- ylmethoxy)carbonyl]amino]-2-methyl-, (2S)-;(9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Pentynyl)-OH
- CAS NO:1050501-65-9
- Molecular Formula: C23H23NO4
- Molecular Weight: 377.43
- EINECS: N/A
- Product Categories: α-Methyl Amino Acids
- Mol File: 1050501-65-9.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 600.2±55.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.222±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.86±0.41(Predicted)
- CAS DataBase Reference: FMoc-α-Me-Gly(Pentynyl)-OH(CAS DataBase Reference)
- NIST Chemistry Reference: FMoc-α-Me-Gly(Pentynyl)-OH(1050501-65-9)
- EPA Substance Registry System: FMoc-α-Me-Gly(Pentynyl)-OH(1050501-65-9)
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Safety Data
- Hazard Codes: F,T
- Statements: 11-23/24/25-39/23/24/25
- Safety Statements: 7-16-36/37-45
- WGK Germany:
- RTECS:
- TSCA: No
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1050501-65-9(Hazardous Substances Data)
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1050501-65-9 Usage
Uses
Used in Pharmaceutical Development:FMoc-α-Me-Gly(Pentynyl)-OH is used as a building block for the synthesis of complex peptides and proteins, enabling the creation of novel bioactive compounds with potential therapeutic applications.
Used in Peptide Synthesis:
FMoc-α-Me-Gly(Pentynyl)-OH is used as a protected amino acid in peptide synthesis, allowing for the stepwise assembly of peptide chains with controlled selectivity and protection of the amino group.
Used in Solid-Phase Peptide Synthesis (SPPS):
In the field of solid-phase peptide synthesis, FMoc-α-Me-Gly(Pentynyl)-OH is used as a key component for the stepwise elongation of peptide chains on an insoluble resin support, providing a robust and efficient method for peptide production.
Used in Chemical Research:
FMoc-α-Me-Gly(Pentynyl)-OH is utilized as a research tool in the development and optimization of new synthetic methods, as well as in the study of peptide structure and function.
Check Digit Verification of cas no
The CAS Registry Mumber 1050501-65-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,0,5,0 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.Calculate Digit Verification of CAS Registry Number 1050501-65:
(9*1)+(8*0)+(7*5)+(6*0)+(5*5)+(4*0)+(3*1)+(2*6)+(1*5)=89
89 % 10 = 9
So 1050501-65-9 is a valid CAS Registry Number.
1050501-65-9Upstream product
1050501-65-9Downstream Products
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FMoc-α-Me-Gly(Pentynyl)-OH
