1050501-88-6

Basic information

• Product Name: 2-Bromo-6-chloropyridin-3-amine
• Synonyms: 2-Bromo-6-chloropyridin-3-amine;3-Amino-2-bromo-6-chloropyridine;3-AMINO-6-CHLORO-2-BROMOPYRIDINE;2-Bromo-6-chloro-3-pyridinamine;2-Bromo-6-chloro-pyridin-3-ylamine
• CAS NO: 1050501-88-6
• Molecular Formula: C₅H₄BrClN₂
• Molecular Weight: 207.45566
• Mol File: 1050501-88-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 330.261 °C at 760 mmHg
• Flash Point: 153.537 °C
• Appearance: /
• Density: 1.834
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -0.12±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-6-chloropyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-6-chloropyridin-3-amine(1050501-88-6)
• EPA Substance Registry System: 2-Bromo-6-chloropyridin-3-amine(1050501-88-6)

Safety Data

• Hazardous Substances Data: 1050501-88-6(Hazardous Substances Data)

Usage

Uses

2-Bromo-6-chloro-3-pyridinamine is a reactant used in the synthesis of kilogram quantities of an akt Kinase inhibitor. It is mainly used as starting material for the production of many pharmaceutical compounds.

Upstream product

• 5350-93-6 6-Chloro-pyridin-3-ylamine 

Downstream Products

• 800401-63-2 5-chloro-1H-pyrrolo[3 ,2-b]pyridine-2-carboxylic acid 
• 31784-71-1 5-chlorothiazolo[5,4-b]pyridin-2-amine 
• 209286-85-1 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine 
• 65156-94-7 5-chloro-1H-pyrrolo[3,2-b]pyridine 
• 1352200-86-2 3-amino-6-chloro-pyridine-2-carboxylic acid ethyl ester 
• 1227958-32-8 tert-butyl (2-bromo-6-chloropyridin-3-yl)carbamate 
• 1199557-04-4 tert-butyl (6-chloro-2-formylpyridin-3-yl)carbamate 
• 1199557-02-2 7-chloro-1-(difluoromethyl)-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridine 
• 1370618-02-2 1-(difluoromethyl)-8-phenyl[1,2,4]triazolo[4,3-a][1,5]-naphthyridin-7-yl trifluoromethanesulfonate 
• 1199557-01-1 1-(difluoromethyl)-8-phenyl[1,2,4]triazolo[4,3-a][1,5]-naphthyridin-7(6H)-one 

Relevant articles and documents

Substituent-Controlled Tailoring of Chalcogen-Bonded Supramolecular Nanoribbons in the Solid State

In this work, we design and synthesize supramolecular 2,5-substituted chalcogenazolo[5,4-β]pyridine (CGP) synthons arranging in supramolecular ribbons at the solid state. A careful choice of the combination of substituents at the 2- and 5-positions on the

NOVEL 1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH HETEROCYCLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS

The present invention is concerned with novel 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherei

1,3 -DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH HETEROCYCLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS

The present invention is concerned with novel 4-substituted 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) tautomers and stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherein R4, R5, Z and Het have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.