105074-27-9Relevant academic research and scientific papers
ELECTROPHILIC CYCLIZATION REACTION OF gem-DIFLUOROOLEFIN DERIVATIVES: SYNTHESES OF 6,6-DIFLUOROTETRAHYDRO-2-PYRONES AND 2,2-DIFLUOROTERTRAHYDROPYRAN via HALOGEN INDUCED CYCLIZATION
Morikawa, Tsutomu,Kumadaki, Itsumaro,Shiro, Motoo
, p. 5144 - 5146 (2007/10/02)
The halocyclization reactions of gem-difluoroolefin derivatives (4, 5 and 8) with iodine in acetonitrile proceed in the 6-endo mode selectively providing 6,6-difluorotetrahydro-2-pyrones (9) and 2,2-difluorotetrahydropyran (10), respectively.KEYWORDS-gem-
