105088-01-5

Upstream product

• 83560-65-0 [2-(α-(dimethylamino)ethyl)-1,1'-ferrocenediyl]phenylphosphine 
• 591-51-5 phenyllithium 

Downstream Products

• 86940-10-5 dichloro(triphenylphosphine)(1-(N,N-α-dimethylaminoethyl)-2-diphenylphosphino-ferrocene)ruthenium(II) 
• 401913-89-1 Os₃H(CO)8(NO₂)C₅H₅FeC₅H₃CHCH₃N(CH₃)2P(C₆H₅)2 
• 74311-58-3 (ScRp)-PPFOAc 
• 193815-90-6 Pd((C₅H₅)Fe(C₅H₃(CH(CH₃)N(CH₃)2)P(C₆H₅)2))(C₄H₂O₃) 
• 193815-95-1 [Pd(η(3)-2-Me-C3H4)Pd((C5H5)Fe(C5H3(CH(Me)NMe2)P(C6H5)2))]OSO2CF3 
• 214825-64-6 PdClCH₃(2-(1-dimethylaminoethyl)-1-diphenylphosphinoferrocene) 
• 258340-41-9 RuCl(C₈H₁₃)((C₅H₅)Fe(C₂₁H₂₃NP)) 

Relevant academic research and scientific papers

The synthesis of α-N,N-dimethyl-1'-diphenylphosphinoferrocenylethylamine and related ligands

Routes to the title compound were explored based on the cleavage of -ferrocenophanes with aryllithium.Thus the cleavage of (ν5-C5H4)Fe(ν5-C5H3(CHMeNMe2)PPh) with phenyllithium affords (ν5-C5H4Li)Fe(ν5-C5H3(CHMeNMe2)PPh2) and (ν5-C5H4PPh2)Fe(ν5-C5H3Li(CHMeNMe2)) in the ratio 15:85.Hydrolysis of this mixture affords the title compound 4.The lithio-ferrocenes can be treated with XER2 to yield other mixed ligands (E = As, P).A route to 4 via (ν5-C5H4PPh2)Fe(ν5-C5H4C(O)Me) was also established but it is complicated by low yields and many side products such as 5-C5H4PPh2)Fe(ν5-C5H4)>2C=CH2.