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Z-D-Val-ONP, also known as Z-D-Valyl-4-nitrophenol, is a chemical reagent specifically designed for enzymatic assays to detect the activity of proteases. It serves as a substrate for serine proteases and is widely used as a chromogenic substrate in protease kinetic studies. The unique design of Z-D-Val-ONP allows it to be cleaved by serine proteases, resulting in the release of the yellow 4-nitrophenol chromophore, which can be quantified spectrophotometrically. This makes Z-D-Val-ONP an indispensable tool in research laboratories for investigating protease activity and inhibition, as well as for studying various biological processes and contributing to drug development.

10512-94-4

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10512-94-4 Usage

Uses

Used in Research Laboratories:
Z-D-VAL-ONP is used as a substrate for serine proteases for the purpose of detecting protease activity. Its ability to be cleaved by these enzymes and release the 4-nitrophenol chromophore allows researchers to quantify protease activity through spectrophotometry, providing valuable insights into enzymatic processes and their regulation.
Used in Protease Kinetic Studies:
Z-D-VAL-ONP is used as a chromogenic substrate to study the kinetics of protease enzymes. By monitoring the release of the 4-nitrophenol chromophore upon cleavage, researchers can determine the reaction rates and mechanisms of protease activity, which is crucial for understanding enzyme function and developing targeted therapies.
Used in Drug Development:
Z-D-VAL-ONP is used as a tool for investigating protease activity and inhibition in the context of drug development. Its application in enzymatic assays helps researchers identify potential drug candidates that can modulate protease activity, contributing to the discovery of new therapeutic agents for various diseases and conditions.
Used in Investigating Biological Processes:
Z-D-VAL-ONP is used as a research tool to study various biological processes involving proteases. By monitoring the activity of these enzymes, scientists can gain a deeper understanding of the roles proteases play in cellular functions, signaling pathways, and disease progression, ultimately leading to advancements in the life sciences.

Check Digit Verification of cas no

The CAS Registry Mumber 10512-94-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,1 and 2 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10512-94:
(7*1)+(6*0)+(5*5)+(4*1)+(3*2)+(2*9)+(1*4)=64
64 % 10 = 4
So 10512-94-4 is a valid CAS Registry Number.

10512-94-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Z-D-valine-p-nitrophenyl ester

1.2 Other means of identification

Product number -
Other names Z-D-VAL-ONP

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10512-94-4 SDS

10512-94-4Upstream product

10512-94-4Relevant academic research and scientific papers

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