105126-40-7

Basic information

• Product Name: (R)-6-Cyclohexyl-dihydro-imidazo[1,5-c]thiazole-5,7-dione
• CAS NO: 105126-40-7
• Molecular Weight: 240.326
• Mol File: 105126-40-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-6-Cyclohexyl-dihydro-imidazo[1,5-c]thiazole-5,7-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-6-Cyclohexyl-dihydro-imidazo[1,5-c]thiazole-5,7-dione(105126-40-7)
• EPA Substance Registry System: (R)-6-Cyclohexyl-dihydro-imidazo[1,5-c]thiazole-5,7-dione(105126-40-7)

Safety Data

• Hazardous Substances Data: 105126-40-7(Hazardous Substances Data)

Upstream product

• 3173-53-3 Cyclohexyl isocyanate 
• 60664-15-5 ethyl (4R)-1,3-thiazolidine-4-carboxylate 
• 42258-90-2 (R)-thiazolidine-4-carboxylic acid methyl ester 

Relevant articles and documents

Immunomodulatory agents: Dioxothiadiazabicyclo[3.3.0]octanes and their 2- spiro derivatives

A series of 6,8-dioxo-3-thia-1,7-diazabicyclo[3.3.0]octanes and a series of 6,8-dioxo-3-thia-1,7-diazabicyclo[3.3.0]octane 2-spiro derivatives were synthesized from L-(-)-R-cysteine ethyl ester in two steps. The synthetic route involved condensation of the amino acid with an appropriate aldehyde or ketone, then a further condensation of the resultant ethyl thiazolidine-4- carboxylate with an isocyanate or an isothiocyanate. The proliferative response to human lymphocyte mitogen (phytohemagglutinin) was used as a primary screening assay for most of the thiadiazabicyclic compounds in comparison with levamisole. Furthermore, the most active compounds were tested for ability to release soluble receptors (sRIL-2) after mitogenic stimulation of T cells and for ability to activate macrophage oxidative metabolism measured by chemiluminescence. Most compounds were active in all three tests and some showed dose-dependent activity.