1051373-76-2

Basic information

• Product Name: 1-(N,N-dimethylsulfamoyl)-5-iodo-2-phenylthio-1H-imidazole
• Synonyms: 1-(N,N-dimethylsulfamoyl)-5-iodo-2-phenylthio-1H-imidazole
• CAS NO: 1051373-76-2
• Molecular Weight: 409.272
• Mol File: 1051373-76-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(N,N-dimethylsulfamoyl)-5-iodo-2-phenylthio-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(N,N-dimethylsulfamoyl)-5-iodo-2-phenylthio-1H-imidazole(1051373-76-2)
• EPA Substance Registry System: 1-(N,N-dimethylsulfamoyl)-5-iodo-2-phenylthio-1H-imidazole(1051373-76-2)

Safety Data

• Hazardous Substances Data: 1051373-76-2(Hazardous Substances Data)

Upstream product

• 78162-58-0 N,N-dimethyl-1H-imidazole-1-sulfonamide 
• 882-33-7 diphenyldisulfane 
• 123914-19-2 1-(N,N-dimethylsulfamoyl)-2-phenylthio-1H-imidazole 

Downstream Products

• 1051373-82-0 4-iodo-1-methyl-2-phenylthio-1H-imidazole 
• 220480-63-7 5-iodo-1-methyl-2-(phenylthio)-1H-imidazole 
• 1051373-78-4 1-(N,N-dimethylsulfamoyl)-4-iodo-2-phenylthio-1H-imidazole 

Relevant articles and documents

Synthesis and biological evaluation of novel imidazole-containing macrocycles

A new family of compounds made of a 5-aryl-1H-imidazole motif included in a macrocycle has been designed and synthesized. The synthesis of the imidazole core makes use of our previously developed method for the regioselective preparation of 1,2,5-trisubstituted imidazoles while the construction of the macrocycle is based on a three steps sequence: SNAr, Suzuki coupling, and RCM reaction. Biological evaluation of synthesized imidazole-containing macrocycles revealed that they display actual binding activity toward A3 adenosine (h) receptor, dopamine D1 (h) receptor, chloride channel (GABA-gated), and choline transporter (h) CHT1.