1051463-24-1
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Basic information
- Product Name: α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol
- Synonyms: α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol;2-[4-(MethylaMino)Methyl-1,3-Thiazole-2-yl] Propane-2-ol;Cobicistat Impurity HCl (2-[4-(Methylamino)methyl-1,3-Thiazole-2-yl] Propane-2-ol HCl);alpha,alpha-Dimethyl-4-[(methylamino)methyl]-2-thiazolemethanol;2-[4-(methylaminomethyl)-1,3-thiazol-2-yl]propan-2-ol
- CAS NO:1051463-24-1
- Molecular Formula: C8H14N2OS
- Molecular Weight: 186.27456
- EINECS: N/A
- Product Categories: Metabolites & Impurities
- Mol File: 1051463-24-1.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol(CAS DataBase Reference)
- NIST Chemistry Reference: α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol(1051463-24-1)
- EPA Substance Registry System: α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol(1051463-24-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1051463-24-1(Hazardous Substances Data)
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1051463-24-1 Usage
Description
α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol is a chemical compound that serves as an impurity in Cobicistat (C633150), an HIV protease inhibitor. It plays a significant role in the pharmaceutical industry due to its association with Cobicistat and its use as a pharmacoenhancer.Used in Pharmaceutical Industry:
α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol is used as a pharmacoenhancer for Cobicistat, an HIV protease inhibitor. It is coadministered with a low-dose ritonavir (R535000) to significantly increase the plasma concentrations of Cobicistat, thereby improving its therapeutic efficacy in the treatment of HIV infection.
Check Digit Verification of cas no
The CAS Registry Mumber 1051463-24-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,1,4,6 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.Calculate Digit Verification of CAS Registry Number 1051463-24:
(9*1)+(8*0)+(7*5)+(6*1)+(5*4)+(4*6)+(3*3)+(2*2)+(1*4)=111
111 % 10 = 1
So 1051463-24-1 is a valid CAS Registry Number.
1051463-24-1Upstream product
1051463-24-1Downstream Products
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α,α-DiMethyl-4-[(MethylaMino)Methyl]-2-thiazoleMethanol
