105176-69-0Relevant academic research and scientific papers
A novel Zn-catalyzed hydroamination of propargylamides: A general synthesis of di- and tri-substituted imidazoles
Pews-Davtyan, Anahit,Beller, Matthias
, p. 2152 - 2154 (2011)
Starting from commercially available amines and propargylamides a variety of substituted imidazoles were synthesized via a novel hydroamination- cyclization sequence. The target compounds are obtained in good to excellent yields in the presence of catalytic amounts of zinc triflate.
Influence of N-substitution in the FVT of pyrazoles
Perez, Jorge D.,Yranzo, Gloria I.,Phagouape, Leonardo M.
, p. 129 - 132 (2007/10/02)
Flash vacuum thermolysis of 1-ethyl (3), 3,5-dimethyl-1-ethyl (4), 1-n-buthyl (5), 1-tert-butyl (6), 3,5-dimethyl-1-phenyl (7) and 1-phenyl-pyrazole (8) was studied.In the N-alkyl derivatives, pyrazole elimination and olefin formation was found.In contrast, phenylderivatives afforded isomerization and nitrogen extrusion.Kinetic parameters for compound 4 are described and a general mechanism including the N-H derivatives is discussed.
