1051901-06-4

Basic information

• Product Name: 4-chloro-N-(3,5-dimorpholin-4-ylphenyl)-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine
• Synonyms: 4-chloro-N-(3,5-dimorpholin-4-ylphenyl)-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine
• CAS NO: 1051901-06-4
• Molecular Weight: 496.009
• Mol File: 1051901-06-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-chloro-N-(3,5-dimorpholin-4-ylphenyl)-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N-(3,5-dimorpholin-4-ylphenyl)-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine(1051901-06-4)
• EPA Substance Registry System: 4-chloro-N-(3,5-dimorpholin-4-ylphenyl)-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine(1051901-06-4)

Safety Data

• Hazardous Substances Data: 1051901-06-4(Hazardous Substances Data)

Upstream product

• 220954-17-6 4,4’-(5-nitro-1,3-phenylene)dimorpholine 
• 2265-94-3 1,3-difluoro-5-nitrobenzene 
• 945397-00-2 N-(3,5-dimorpholin-4-ylphenyl)formamide 
• 945397-21-7 3,5-di(morpholino)aniline 
• 945397-01-3 4-chloro-N-(3,5-dimorpholin-4-ylphenyl)pyrimidin-2-amine 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 1051899-64-9 N₂-(3,5-dimorpholinophenyl)-N₂-(4-methoxybenzyl)-N₄-(3-methoxyphenyl)pyrimidine-2,4-diamine 
• 1051901-20-2 C₃₂H₃₄F₂N₆O₃ 
• 1051898-81-7 N₂-(3,5-dimorpholinophenyl)-N₄-isopropyl-N₄-(3-methoxyphenyl)pyrimidine-2,4-diamine 
• 1051897-42-7 N'-(2,3-difluorophenyl)-N-(3,5-dimorpholin-4-ylphenyl)-N'-methyl-pyrimidine-2,4-diamine 
• 1051899-65-0 N₂-(3,5-dimorpholinophenyl)-N₄-isopropyl-N₂-(4-methoxybenzyl)-N₄-(3-methoxyphenyl)pyrimidine-2,4-diamine 
• 1104455-28-8 N₂-(3,5-dimorpholinophenyl)-N₂-(4-methoxybenzyl)-N₄-(5-methoxypyridin-3-yl)pyrimidine-2,4-diamine 

Relevant articles and documents

2,4-DIAMINO-PYRIMIDINE DERIVATIVES

The invention concerns compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R1, Q, R3, and R4 are as defined in the description. The present invention also relates to processes for the preparation ofsuch compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of EphB4 kinases.