105202-50-4Relevant academic research and scientific papers
Synthesis of Heterocyclic Compounds XLIX . An Unexpected Synthesis of Isoxazolamines
Ciller, J. A.,Seoane, C.,Soto, J. L.
, p. 1663 - 1665 (2007/10/02)
Reaction of 3-aryl-1-phenyl-2-nitropropenones 1 with potassium cyanide leads to 4-aryl-3-benzoyl-5-isoxazolamines 5 in a one-step process involving the formal reduction of the nitro group followed by nucleophilic attack at the cyano group.Treatment of the isoxazolamine with an aromatic aldehyde yields the corresponding N-arylideneisoxazolamine.
