1052074-60-8

Basic information

• Product Name: (7'S,8S,8'R)-4,4'-dihydroxy-8'-hydroxymethyl-3,3'-dimethoxylignano-9,7'-lactone
• Synonyms: (7'S,8S,8'R)-4,4'-dihydroxy-8'-hydroxymethyl-3,3'-dimethoxylignano-9,7'-lactone
• CAS NO: 1052074-60-8
• Molecular Weight: 374.39
• Mol File: 1052074-60-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (7'S,8S,8'R)-4,4'-dihydroxy-8'-hydroxymethyl-3,3'-dimethoxylignano-9,7'-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: (7'S,8S,8'R)-4,4'-dihydroxy-8'-hydroxymethyl-3,3'-dimethoxylignano-9,7'-lactone(1052074-60-8)
• EPA Substance Registry System: (7'S,8S,8'R)-4,4'-dihydroxy-8'-hydroxymethyl-3,3'-dimethoxylignano-9,7'-lactone(1052074-60-8)

Safety Data

• Hazardous Substances Data: 1052074-60-8(Hazardous Substances Data)

Upstream product

• 689277-84-7 (7'S,8R,8'R)-4,4'-bis(tert-butyldimethylsilanyloxy)-7'-hydroxy-3,3'-dimethoxylignano-9,9'-lactone 

Relevant articles and documents

Stereochemistry and rearrangement reactions of hydroxylignanolactones

Various conflicting data on the rearrangement and absolute stereochemistry of hydroxylignano-9,7′-lactones are resolved using 18O labeled compounds, also confirmed by an X-ray analysis of a pure lignano-9,7′- lactone enantiomer, obtained for the first time. Under NaH/DMF rearrangement conditions a silyl protected hydroxylignano-9,9′-lactone underwent an unexpected silyl migration. The Royal Society of Chemistry 2008.