105219-44-1

Basic information

• Product Name: 3-(3,5-DIFLUORO-4-METHOXYPHENYL)PROPIONIC ACID
• Synonyms: 3-(3,5-DIFLUORO-4-METHOXYPHENYL)PROPIONIC ACID
• CAS NO: 105219-44-1
• Molecular Formula: C₁₀H₁₀F₂O₃
• Molecular Weight: 216.19
• Mol File: 105219-44-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 83-86℃
• Appearance: /
• CAS DataBase Reference: 3-(3,5-DIFLUORO-4-METHOXYPHENYL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,5-DIFLUORO-4-METHOXYPHENYL)PROPIONIC ACID(105219-44-1)
• EPA Substance Registry System: 3-(3,5-DIFLUORO-4-METHOXYPHENYL)PROPIONIC ACID(105219-44-1)

Safety Data

• Hazardous Substances Data: 105219-44-1(Hazardous Substances Data)

Upstream product

• 7440-05-3 palladium 

Downstream Products

• 105219-45-2 3-(3,5-difluoro-4-methoxyphenyl)propan-1-ol 

Relevant articles and documents

4-Aralkyl-5-substituted-1,2,4-triazole-5-thiols

Compounds of formula (I) and pharmaceutically acceptable salts thereof are described in which, n is 0 to 5; X1 to X5 are any accessible combination of hydrogen, halogen, C1 6alkyl, C1 6alkoxy, cyano, nitro, SONH2, SO2NH2, SO2CH3, SO2CH2F, SO2CHF2, SO2CF3, CF3, CHO, OH, CH2OH, CO2H, or CO2CpH2p+1wherein p is 1 to 4; R1 is phenyl substituted by X1 to X5, C1 4alkyl, C3 6cycloalkyl, or an arylC1 4alkyl group substituted by X1 to X5; R2 is hydrogen, C1 4alkyl or (CH2)m-CO2R3; m is 0 to 5; and R3 is H or C1 4alkyl. These compounds are dopamine-β-hydroxylase inhibitors. Pharmaceutical compositions are described as are methods of use. Processes for the preparation of these compounds are described.