1052209-96-7

Basic information

• Product Name: (5S)-5-Phenyl-3-morpholinone
• Synonyms: (5S)-5-Phenyl-3-morpholinone;(S)-5-Phenylmorpholin-3-one;(5S)-5-Phenylmorpholin-3-one
• CAS NO: 1052209-96-7
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177
• Mol File: 1052209-96-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 1.149
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (5S)-5-Phenyl-3-morpholinone(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-5-Phenyl-3-morpholinone(1052209-96-7)
• EPA Substance Registry System: (5S)-5-Phenyl-3-morpholinone(1052209-96-7)

Safety Data

• Hazardous Substances Data: 1052209-96-7(Hazardous Substances Data)

Usage

General Description

(5S)-5-Phenyl-3-morpholinone, also known as EMDO or N-phenylmorpholin-3-one, is a chemical compound with a molecular formula of C11H11NO2. It is a white crystalline powder that is soluble in organic solvents but insoluble in water. (5S)-5-Phenyl-3-morpholinone is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It has also been studied for its potential use in the treatment of neurological disorders and cancer. Additionally, (5S)-5-Phenyl-3-morpholinone is known to have mild sedative and analgesic effects, making it useful in the development of new drugs for pain management. However, it is important to handle this compound with caution as it may have toxic effects if ingested or inhaled in large amounts.

Upstream product

• 1373883-16-9 methyl 2-(2-chloroacetamido)-2-phenylacetate 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 20989-17-7 (2S)-2-phenylglycinol 
• 291545-74-9 (S)-2-chloro-N-(2-hydroxyl-1-phenylethyl)acetamide 

Downstream Products

• 914299-79-9 (3S)-3-phenylmorpholine 
• 1607483-12-4 C₁₅H₁₉NO₄ 
• 1607483-13-5 C₁₅H₂₁NO₄ 
• 1607483-14-6 C₁₆H₂₃NO₄ 
• 1607483-16-8 C₁₇H₂₆NO₆P 

Relevant articles and documents

SUBSTITUTED MORPHOLINE DERIVATIVES AS ROR GAMMA MODULATORS

The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, X1, X2, m and n are as defined herein, which are active as modulators of retinoid-related orphan receptor gamma t (RORyt). These compounds prevent, inhibit, or suppress the action of RORyt and are therefore useful in the treatment of RORyt mediated diseases, disorders, syndromes or conditions such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer. (I)

TRICYCLIC MODULATORS OF TNF SIGNALING

The invention provides tricyclic heterocyclic compounds, pharmaceutically acceptable salts, prodrugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the invention may be useful for treating immunological and oncological conditions.

Amine-promoted asymmetric (4+2) annulations for the enantioselective synthesis of tetrahydropyridines: A traceless and recoverable auxiliary strategy

Gone, without a trace: The in situ reaction of 2-(acetoxymethyl)buta-2,3- dienoate and a secondary amine produces a 2-methylene-3-oxobutanoate equivalent that can be used in asymmetric [4+2] annulations with N-tosylimines to provide tetrahydropyridines in