105224-25-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Ethoxymethylene-3-oxobutanenitrile is used as a building block for the synthesis of various pharmaceuticals. It plays a crucial role in the development of new drugs and medicines, contributing to the advancement of healthcare and treatment options.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Ethoxymethylene-3-oxobutanenitrile is used as a building block for the synthesis of various agrochemicals. It helps in the development of new pesticides, herbicides, and other agricultural chemicals, enhancing crop protection and productivity.
Used as a Reagent in Organic Synthesis:
2-Ethoxymethylene-3-oxobutanenitrile is utilized as a reagent in organic synthesis, facilitating various chemical reactions and processes. Its unique properties make it a valuable component in the synthesis of complex organic compounds, contributing to the advancement of organic chemistry and its applications in various fields.

Upstream product

• 2469-99-0 Cyanoaceton 
• 122-51-0 orthoformic acid triethyl ester 
• 108-24-7 acetic anhydride 

Downstream Products

• 18093-88-4 5-methyl-1-phenyl-1H-pyrazole-4-carbonitrile 
• 1139872-21-1 methyl 3-cyano-5-heptyl-6-hydroxy-2-methylbenzoate 
• 1139872-19-7 methyl 3-cyano-5-hexyl-6-hydroxy-2-methylbenzoate 
• 1139872-17-5 methyl 3-cyano-6-hydroxy-2,5-dimethylbenzoate 
• 1139872-16-4 ethyl 3-cyano-6-hydroxy-2-methylbenzoate 
• 1139872-18-6 ethyl 3-cyano-5-ethyl-6-hydroxy-2-methylbenzoate 
• 1174012-37-3 methyl 3-butyl-5-cyano-2-hydroxy-6-methylbenzoate 
• 1174012-35-1 methyl 3-cyano-6-hydroxy-2-methylbenzoate 

Relevant academic research and scientific papers

Fused tricyclic compound and application in medicines

The invention relates to a condensed tricyclic compound and application in medicines, particularly to application of the condensed tricyclic compound as a medicine for treating and/or preventing hepatitis B. Specifically the present invention relates to a

Process for the preparation of substituted pyrimidine derivatives

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H4 receptor modulators, and to intermediates in H4 modulator synthesis.

First synthesis of 5-cyanosalicylates by formal [3+3] Cyclocondensations of 1,3-Bis(silyloxy)-1,3-butadienes

A variety of functionalized benzonitriles were regioselectively prepared by formal [3+3] cyclocondensation of 1,3-bis(silyloxy)-1,3-butadienes with 3-ethoxy- and 3-silyloxy-2-cyano-2-en-1-ones. Georg Thieme Verlag Stuttgart.

First synthesis of functionalized benzonitriles by formal [3+3] cyclocondensations of 1,3-bis(silyloxy)buta-1,3-dienes

A variety of functionalized benzonitriles were regioselectively prepared by formal [3+3] cyclocondensation of 1,3-bis(silyloxy) buta-1,3-dienes with 3-ethoxy- and 3-silyloxy-2-cyano-2-en-1-ones. Georg Thieme Verlag Stuttgart.

4-AMINOETHYLENE DERIVATIVES OF 2-METHYLBENZOTRIAZOLE

N-Methylation of 4(7)-nitrobenzotriazole (I) afforded a mixture of three isomers; one of them, 4-nitro-2-methylbenzotriazole (II) could easily be isolated.Catalytical hydrogenation of II led to the corresponding amine which in turn, afforded products of nucleophilic substitution IVa-IVi on reaction with alkoxymethylene derivatives IIIa - IIIi.Thermal cyclocondensation of IVi yielded 7-ethoxycarbonyl-6,9-dihydro-6-oxo-2-methyl-2H-triazoloquinoline (V).The structure of all products was deduced from the IR, UV, 1H and 13C NMR spectral data.