10524-04-6 Usage
Description
(1R,2R)-cis-1-(ChloroMethyl)-2-Methylcyclopropane is an organic compound characterized by its unique cyclopropane structure with a chloromethyl group at the 1-position and a methyl group at the 2-position. (1R,2R)-cis-1-(ChloroMethyl)-2-Methylcyclopropane is notable for its potential applications in various fields due to its distinct chemical properties.
Uses
Used in Chemical Synthesis:
(1R,2R)-cis-1-(ChloroMethyl)-2-Methylcyclopropane is used as a key intermediate in the synthesis of monoand bi-cyclic radicals containing the cyclopropylmethyl group. These radicals are essential for various chemical reactions and can be employed as mechanistic probes to study reaction mechanisms and kinetics.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1R,2R)-cis-1-(ChloroMethyl)-2-Methylcyclopropane can be utilized as a starting material for the development of new drugs with potential therapeutic applications. The unique structure of this compound allows for the creation of novel molecular entities that can target specific biological pathways.
Used in Material Science:
(1R,2R)-cis-1-(ChloroMethyl)-2-Methylcyclopropane may also find applications in material science, where its unique structural features can be exploited to develop new materials with specific properties, such as improved stability or reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 10524-04-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,2 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10524-04:
(7*1)+(6*0)+(5*5)+(4*2)+(3*4)+(2*0)+(1*4)=56
56 % 10 = 6
So 10524-04-6 is a valid CAS Registry Number.
10524-04-6Relevant articles and documents
Electrophilic cleavage of cyclopropylmethystannanes: An experimental comparison of σ-σ and σ-π conjugation
Lucke, Andrew J.,Young, David J.
, p. 3579 - 3583 (2007/10/03)
(Chemical Equation Presented) Cyclopropylmethyltrimethylstannanes undergo electrophilic cyclopropane cleavage in chloroform with simple inorganic electrophiles (H+, SO2, I2) in a homologous reaction to the SE′ cleavage of allylic stannanes. The σ-σ conjugation between the carbon-tin bond and cyclopropane orbitals observed spectroscopically in the parent cyclopropylmethyltrimethylstannane is responsible for a rate enhancement of ca. 102 toward iodinolysis, relative to comparable alkyl stannanes. This acceleration is considerably less, however, than the ca. 109-fold rate enhancement provided by the corresponding σ-π conjugation in allylic stannanes. Methanol-tin coordination appears to reduce the activating influence of the metal, promoting methyl cleavage over cyclopropane fission with acid and iodine. Decreased σ-σ conjugation can also explain the decreased reactivity of cyclopropyltriphenylstannane compared with its trimethyltin counterpart. Cyclopropylmethylstannanes do not undergo the synthetically useful addition of aldehydes under conditions that facilitate the corresponding reaction of allylic stannanes.
