105243-29-6

Upstream product

• 100924-00-3 C₂₄H₄₇Al 
• 105243-21-8 (R)-4-formyl-2-phenyl-1,3-oxazolin-2-ene 
• 825-60-5 benzimidic acid ethyl ester 
• 105308-52-9 (R)-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 100923-98-6 (E)-6-methyl-pentadec-5-en-1-yne 

Downstream Products

• 105308-56-3 (4E,8E,2R,3R,2'R)-N-2'-acetoxyhexadecanoyl-1-O-benzoyl-9-methyl-4,8-sphingadienine 
• 105308-55-2 (4E,8E,2R,3R,2'S)-N-2'-acetoxyhexadecanoyl-1-O-benzoyl-9-methyl-4,8-sphingadienine 

Relevant academic research and scientific papers

Novel aliphatic compounds, process for their preparation and their usage

The present invention provides an aliphatic compound represented by the following formula (I) or pharmacologically acceptable salts thereof: where n denotes an integer of 1 to 11, and 1 denotes an integer of 1 to 16, the aliphatic compound being an optical isomer of the (2R,3S,2′S) configuration when the 8-position thereof is a double bond, or an optical isomer of the (2S,3R,2′RS) configuration when the 8-position is a single bond; methods for producing the compound or pharmacologically acceptable salts thereof; and uses of the compound in the treatment of cardiovascular diseases (e.g. arteriosclerosis, cardiac diseases), cancer, rheumatism, diabetic retinopathy, and respiratory diseases.

Synthesis and Biological Activity of the Isomers and Analogs of (4E,8E,2S,3R,2'R)-N-2'-Hydroxyhexadecanoyl-9-methyl-4,8-sphingadienine, the Ceramide Portion of the Fruiting-inducing Cerebroside in a Basidiomycete Schizophyllum commune

The title compounds were synthesized by employing 2-aminohexadecanoic acid and serine as the chiral sources, and served for an assay of fruiting-inducing activity on Schizophyllum commune.The structure-bioactivity relationship among closely related synthetic ceramides is discussed.