105250-85-9 Usage
General Description
H-TYR-GLY-PHE-GLY-GLY-OH is a pentapeptide composed of the amino acids tyrosine (TYR), glycine (GLY), and phenylalanine (PHE). It has a free carboxyl group (OH) at the C-terminus. This peptide may exhibit biological activity or serve as a building block for larger peptides or proteins. TYR and PHE are aromatic amino acids, while GLY is the simplest amino acid with a hydrogen atom as its side chain. The sequence and composition of H-TYR-GLY-PHE-GLY-GLY-OH are important for understanding its potential functions and interactions within biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 105250-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,2,5 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 105250-85:
(8*1)+(7*0)+(6*5)+(5*2)+(4*5)+(3*0)+(2*8)+(1*5)=89
89 % 10 = 9
So 105250-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C24H29N5O7/c25-18(10-16-6-8-17(30)9-7-16)23(35)27-13-21(32)29-19(11-15-4-2-1-3-5-15)24(36)28-12-20(31)26-14-22(33)34/h1-9,18-19,30H,10-14,25H2,(H,26,31)(H,27,35)(H,28,36)(H,29,32)(H,33,34)/t18-,19-/m0/s1
105250-85-9Relevant articles and documents
Kilogram-Scale Synthesis of Osteogenic Growth Peptide (10-14) Using a Fragment Coupling Approach
Zhang, Teng,Chen, Zhenxing,Tian, Yan,Han, Bin,Zhang, Ning,Song, Wei,Liu, Zhulan,Zhao, Jinli,Liu, Jianli
, p. 1257 - 1262 (2015)
Kilogram-scale synthesis of a bioactive pentapeptide in solution by "3 + 2" fragment coupling strategy has been successively accomplished in the development of OGP (10-14), a minimal OGP-derived sequence that retains the full proliferative activity of the osteogenic growth peptide. The synthetic scheme, coupling conditions, and scaling-up of the process are systematically studied; the epimerization of the tripeptide fragment and pentapeptide are also evaluated.
SYNTHESIS OF HISTORPHINE AND ITS PHOSPHONE ANALOG
Solodenko, V. A.,Kasheva, T. N.,Kukhar', V. P.
, p. 2307 - 2308 (2007/10/02)
-
