105253-94-9

Upstream product

• 857592-14-4 (4,5-dimethoxy-2-methyl-benzyliden)-aniline 
• 141-82-2 malonic acid 
• 7721-62-2 4,5-dimethoxy-2-methylbenzaldehyde 
• 494-99-5 1,2-dimethoxy-4-methylbenzene 
• 108-24-7 acetic anhydride 

Downstream Products

• 131035-53-5 (4,5-Dimethoxy-2-methyl-phenyl)-propynoic acid 
• 131035-52-4 methyl 3-(4,5-dimethoxy-2-methylphenyl)propiolate 
• 131035-51-3 ethyl 2,3-dibromo-3-(4,5-dimethoxy-2-methylphenyl)propionate 

Relevant academic research and scientific papers

ANTI-HIV COMPOUNDS

This invention provides, among other things, tetrahydroisoquinolines useful for treating viral infections, pharmaceutical formulations containing such compounds, as well as methods of inhibiting the replication of a virus, such as HIV, or treating a disease, such as AIDS.

Synthesis based on Cyclohexadienes: Part 4. Novel Synthesis of the 6-Aryl-2,4-dimethoxybenzoates. Alternariol and Methyl Trimethylaltenusin

A novel method for the preparation of 6-aryl-2,4-dimethoxybenzoic acids involving the Alder-Rickert reaction of 1,5-dimethoxycyclohexa-1,4-dienes and arylpropiolic esters is described.This strategy has been extended to the synthesis of the mould metabolite alternariol and methyl trimethylaltenusin.