1052617-38-5

Basic information

• Product Name: 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
• Synonyms: 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
• CAS NO: 1052617-38-5
• Molecular Formula: C6H6F2N2O2
• Molecular Weight: 176.1208464
• Mol File: 1052617-38-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID(1052617-38-5)
• EPA Substance Registry System: 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID(1052617-38-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 1052617-38-5(Hazardous Substances Data)

Usage

General Description

3-(difluoromethyl)-1-methyl-1H-pyrazole-5-carboxylic acid is a compound with a chemical structure consisting of a pyrazole ring with a carboxylic acid group attached at the 5th position, as well as a difluoromethyl and a methyl group attached at the 3rd and 1st positions, respectively. 3-(difluoromethyl)-1-methyl-1H-pyrazole-5-carboxylic acid has potential applications in pharmaceuticals and agrochemicals due to its unique structure and properties. It may be used in the development of new drugs or as a building block in the synthesis of other organic compounds with desired properties. Additionally, its fluorinated moiety may provide increased stability and bioavailability, making it an interesting target for further research and development in the field of medicinal and agricultural chemistry.

Upstream product

• 1031351-95-7 3-formyl-1-methyl-1H-pyrazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

Regioselective Synthesis of Functionalized 3- or 5-Fluoroalkyl Isoxazoles and Pyrazoles from Fluoroalkyl Ynones and Binucleophiles

A facile synthetic route toward either 3- or 5-fluoroalkyl-substituted isoxazoles or pyrazoles containing an additional functionalization site was developed and applied on a multigram scale. The elaborated approach extends the scope of fluoroalkyl substituents for introduction into the heterocyclic moiety, and uses convenient transformations of the side chain for incorporation of fluoroalkyl-substituted azoles into the structures of biologically active molecules. The utility of the obtained building blocks for isosteric replacement of alkyl-substituted isoxazole and pyrazole was shown by the synthesis of fluorinated Isocarboxazid and Mepiprazole analogues.

MODULATORS OF THE INTEGRATED STRESS PATHWAY

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

MODULATORS OF THE INTEGRATED STRESS PATHWAY

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.