105262-92-8Relevant academic research and scientific papers
RHODIUM CARBENOID MEDIATED CYCLISATIONS. PART 2. SYNTHESIS OF CYCLIC ETHERS
Heslin, Julie C.,Moody, Christopher J.
, p. 1417 - 1424 (2007/10/02)
Alkylation of the dianion of methyl acetoacetate with the t-butyldimethylsilyl protected α,ω-halogeno alcohols (1)-(9) gives the β-keto esters (1) which are converted into the diazo alcohols (3) by diazo transfer and desilylation.Rhodium carbenoid cyclisa
SYNTHESIS OF CYCLIC ETHERS BY RHODIUM CARBENOID CYCLISATION
Heslin, Julie C.,Moody, Christopher J.,Slawin, Alexandra M. Z.,Williams, David J.
, p. 1403 - 1406 (2007/10/02)
Treatment of the diazocarbonyl compounds (2), readily prepared in 3 steps from methyl acetoacetate, with a catalytic amount of rhodium (II) acetate, leads to the formation of the cyclic ethers (3).
