1052707-21-7

Basic information

• Product Name: (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride
• Synonyms: (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride;(1S,2S)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride;(1S,2S)-1,2-Bis[4-(dimethylamino)phenyl]-1,2-ethanediamine hydrochloride (1:4)
• CAS NO: 1052707-21-7
• Molecular Formula: C18H30Cl4N4
• Molecular Weight: 444.2696
• Mol File: 1052707-21-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 209-225 °C
• Appearance: /
• CAS DataBase Reference: (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride(1052707-21-7)
• EPA Substance Registry System: (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride(1052707-21-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37
• Hazardous Substances Data: 1052707-21-7(Hazardous Substances Data)

Usage

General Description

The chemical compound (1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride, also known as FURA-2 AM, is a synthetic dye used in biological research as a fluorescent calcium indicator. It is commonly used to monitor calcium ion concentrations in living cells and tissues. FURA-2 AM is a cell-permeant acetoxymethyl ester of FURA-2, which allows it to easily enter cells and be cleaved by intracellular esterases, resulting in the release of the active fluorescent dye. The compound is typically used in combination with fluorescence microscopy or flow cytometry to visualize and quantify changes in calcium levels within cells, and it has been instrumental in advancing our understanding of various physiological processes and disease pathways related to calcium signaling.