1052725-34-4 Usage
Chemical structure
A ribose derivative with acetyl and benzyl groups attached to its hydroxyl groups, and a vinyl group attached at the 4-C position.
Parent compound
β-D-ribofuranose, a naturally occurring sugar.
Functional groups
Acetyl (COCH3), benzyl (C6H5CH2), and vinyl (C=CH2) groups.
Stereochemistry
β-D-ribofuranose, indicating the specific arrangement of atoms in the molecule.
Solubility
Generally soluble in organic solvents like chloroform, dichloromethane, and methanol.
Stability
Stable under normal laboratory conditions, but sensitive to moisture and heat.
Reactivity
The acetyl and benzyl groups can be removed or modified through various chemical reactions, allowing for the synthesis of a wide range of derivatives.
Applications
Used as a building block in organic synthesis for the creation of more complex molecules, particularly in the fields of pharmaceuticals, agrochemicals, and materials science.
Derivatives
The unique structure of 1,2-di-O-acetyl-3,5-di-O-benzyl-4-C-vinyl-β-D-ribofuranose allows for the manipulation of its functional groups to create a variety of derivatives with different properties and applications.
Synthesis
Typically synthesized through the selective protection and deprotection of hydroxyl groups in β-D-ribofuranose, followed by the introduction of the vinyl group at the 4-C position.
Check Digit Verification of cas no
The CAS Registry Mumber 1052725-34-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,2,7,2 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1052725-34:
(9*1)+(8*0)+(7*5)+(6*2)+(5*7)+(4*2)+(3*5)+(2*3)+(1*4)=124
124 % 10 = 4
So 1052725-34-4 is a valid CAS Registry Number.
1052725-34-4Relevant articles and documents
Synthesis of 6′-branched locked nucleic acid by a radical TEMPO-scavanged stereoselective mercury cyclization
Enderlin, Gerald,Nielsen, Poul
, p. 6891 - 6894 (2008/12/22)
(Chemical Equation Presented) A 6′(R)-hydroxymethyl derivative of the locked nucleic acid (LNA)-thymidine monomer has been synthesized by a stereoselective mercury cyclization and subsequent use of TEMPO as a radical scavenger. This compound was converted to an azide derivative, which in a Huisgen-type [3 + 2] cycloaddition afforded a double-headed nucleoside with a triazole linking an additional thymine to the opposition of the LNA-nucleoside monomer.
