105273-83-4Relevant articles and documents
Assessment of elementary derivatives of 1,5-benzodiazepine as anticancer agents with synergy potential
Gawandi, Sinthiya J.,Joshi, Shrinivas,Pissurlenkar, Raghuvir R.,Shingade, Sunil,desai, Vidya G.
, (2021/12/10)
Herein, we designed and synthesized 1,5-benzodiazepines as a lead molecule for anticancer activity and as potent synergistic activity with drug Methotrexate. Working under the framework of green chemistry principles, series of 1,5-benzodiazepine derivativ
DERIVATIVES OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE BASED ON SUBSTITUTED 1,2-PHENYLENEDIAMINES AND ACETYLARENES
Orlov, V. D.,Desenko, S. M.
, p. 1377 - 1381 (2007/10/02)
Derivatives of 2,3-dihydro-1H-1,5-benzodiazepine were obtained by the reaction of 4-chloro-, 4-bromo- 3,5-dichloro, and 4-cyano-substituted ortho-phenyl-enediamines with 4-R-acetophenones in the presence of concentrated sulfuric acid.Electronwithdrawing g