105281-00-3

Basic information

• Product Name: Toluene-4-sulfonic acid (2R,3R,4S,5R)-5-(4-amino-5-iodo-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester
• Synonyms: Toluene-4-sulfonic acid (2R,3R,4S,5R)-5-(4-amino-5-iodo-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester
• CAS NO: 105281-00-3
• Molecular Weight: 525.296
• Mol File: 105281-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (2R,3R,4S,5R)-5-(4-amino-5-iodo-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (2R,3R,4S,5R)-5-(4-amino-5-iodo-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester(105281-00-3)
• EPA Substance Registry System: Toluene-4-sulfonic acid (2R,3R,4S,5R)-5-(4-amino-5-iodo-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester(105281-00-3)

Safety Data

• Hazardous Substances Data: 105281-00-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 69123-90-6 fiacitabine 

Downstream Products

• 105281-15-0 1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine 
• 105281-20-7 1-(2,5-dideoxy-2-fluoro-5-thio-β-D-arabinofuranosyl)-5-iodoacetate 
• 105281-13-8 1-(5-amino-2,5-dideoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine 

Relevant articles and documents

Nucleosides. 139. Synthesis and Anticytomegalovirus and Antiherpes Simplex Virus Activity of 5'-Modified Analogues of 2'-Fluoroarabinosylpyrimidine Nucleosides

In order to determine if modification of the 5'-position reduces or abolishes the antiviral activity of 2'-fluoro-5-iodo-ara-C (FIAC), 2'-fluoro-5-iodo-ara-U (FIAU), or 2'-fluoro-5-methyl-ara-U (FMAU) against human cytomegalovirus (HCMV) and herpes simple